Articles tagged Mouse & Rat
(28 results)

Fascinating discoveries sometimes emerge from the most daunting of experimental roadblocks. Designed to generate over 1,000 recombinant inbred mice lines for genetic mapping, the Collaborative Cross (CC) project unearthed astounding variation in male fertility when nearly 95% of the highly inbred CC lines went extinct. As part of the Multiparental Populations series in the June…

Multiparental populations (MPPs) have brought a new era in mapping complex traits, as well as new analytical challenges. To face these challenges and encourage innovation, the GSA journals launched the ongoing Multiparental Populations series in 2014. This month’s issues of GENETICS and G3 feature a bumper 16 MPP articles, timed to celebrate a new easy-to-use…

Guest post by Teresa Bonello It was 1984 and the first cloning of the homeobox sequence in Drosophila had just been reported. Newly-minted postdoc Denis Duboule was called into the office of his mentor, Pierre Chambon, and asked if he wanted to lead his own investigation looking for Hox clusters in mice. What followed was…

#TAGC16 Shorts are brief summaries of presentations at The Allied Genetics Conference, a combined meeting of seven genetics research communities held July 13-17, 2016 in Orlando, Florida. One of the earliest events in development is the switch to self sufficiency. Soon after an egg is fertilized, the new individual must activate its genome and cease…

Model Organism Databases (MODs) and the Gene Ontology Consortium play a crucial “behind-the-scenes” role in the work of model organism geneticists and many other biomedical researchers. This guest post by the newly-formed Alliance of Genome Resources announces the group’s intention to integrate the efforts of the MODs and other genome resources. You can learn more…

New Faculty Profiles showcase GSA members who are establishing their first independent labs. If you’d like to be considered for a profile, please complete this form on the GSA website.   Folami Ideraabdullah Assistant Professor (since 2013) Department of Genetics University of North Carolina School of Medicine Lab website   Research program: My lab studies epigenetic mechanisms…

New Faculty Profiles showcase GSA members who are establishing their first independent labs. If you’d like to be considered for a profile, please complete this form on the GSA website.   Jennifer Garrison Assistant Professor Buck Institute for Research on Aging Lab website   Research program: We study the relationship between the anatomy of neural…

Expectant mothers undergo vast physiological changes during pregnancy and in the months following the birth of their children. In humans, fat and total body water increase; plasma protein concentrations decrease; and blood volume, cardiac output, and blood flow to the kidneys increase. We know that these processes are controlled by the central nervous system. What…

In response to concerns that have been raised about reproducibility in biomedical research, the Federation of American Societies for Experimental Biology (FASEB) invited experts, delegates from its member societies (including GSA), and representatives from the National Institutes of Health (NIH), National Science Foundation (NSF), and other stakeholders to discuss general factors that may impede the ability to…

Chickens that “chicken out” in unfamiliar surroundings may shed light on anxiety in humans, according to research published in the January 2016 issue of the journal GENETICS. Domestic chickens are much less anxious than their wild cousins, the red junglefowl. The new research identifies genes that contribute to this behavioral variation and reveals that several…

GSA members are well represented among the winners of FASEB’s fourth annual BioArt competition: 4 of the 11 winning images were submitting by our members. The BioArt competition seeks to share the beauty and excitement of biological research with the public by featuring captivating images and illustrations that represent cutting-edge life science research. All winning…