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Articles tagged Genetics Journal
(301 results)
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The Genetics Society of America and Figshare partner to promote data underlying publications
The GSA Journals are excited to announce that we have partnered with Figshare to archive supplemental material and data from papers published in GENETICS and G3: Genes|Genomes|Genetics. When you publish a paper in GENETICS or G3, you help to catalyze scientific advances by sharing experimental reagents, results, and interpretations. For these articles to have the…
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Three GENETICS articles from 2017 recognized with Editors’ Choice Awards
Congratulations to the winners of the Editors’ Choice Awards for outstanding articles published in GENETICS in 2017! The journal’s Editorial Board considered a diverse range of articles, finding many papers worthy of recognition. After much deliberation, they settled on one exceptional article for each of the three award categories: molecular genetics, quantitative genetics, and population and evolutionary genetics.…
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Zooming in: population genetics on a mitochondrial level
The mitochondria powering your cells are not all genetically identical. Genetic variation across the mitochondria of a single individual is common. This diversity is called mitochondrial heteroplasmy, and it plays an important role in the severity of mitochondrial disease. Problematically, the complexities of mitochondrial inheritance makes it extremely difficult to predict how this diversity is…
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From fish tank to bedside
Yeast and zebrafish are among the lab organisms being recruited to the search for rare disease cures. Rare diseases are not so rare. About 300 million people worldwide live with the more than 7000 individual diseases that are designated “rare” by the US government. But because each of these affect so few individuals, the usual…
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Worm studies reveal cells on the move
Consider the papercut—a minor injury best known for the disproportionate amount of pain it can cause. That a wound so inconsequential can sting so terribly is curious, but perhaps even more surprising is the fact that it heals at all. To heal a wound, even one as trivial as a papercut, the cells involved in…
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Behind the cover: Drosophila Halloween genes
Fruit fly mutants can sometimes be grisly. Ecdysteroid hormones control aspects of fly development, including molting and metamorphosis; because aberrations in these genes lead to embryos with a ghastly appearance, they have been collectively dubbed “Halloween genes.” In a study published in GENETICS, Uryu et al. investigated how the expression of these genes is regulated.…
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Using CRISPR for tissue-specific gene knockouts in Xenopus
Why study human diseases in frogs? For starters, 79% of genes implicated in human disease have orthologs in the African clawed frog Xenopus laevis. Frogs also produce hundreds of embryos that can be grown in a dish, meaning they can be manipulated in ways that are impractical on a large scale in mammals. For example,…
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Tales told by ancient human DNA
Archaeologists have long known how to extract millennia-old stories from a single tooth buried in an ancient ruin—and now geneticists have the tools to join them. Advances made in the last several years have enabled researchers to sequence tiny amounts of DNA preserved in very old specimens, such as the material inside a tooth from…
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Battle-scarred flies help us understand the genetics of aggression
Whether it’s a battle over territory or a brawl over a sports game, aggressive behavior is a hallmark of the animal kingdom. The influence genetics has on aggression is undeniable—but the process of determining the genes involved has been frustratingly slow. To better understand genetic factors involved in aggression, some researchers have turned to male…
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February GENETICS Highlights
Check out the February issue of GENETICS by looking at the highlights or the full table of contents! ISSUE HIGHLIGHTS Comparative oligo-FISH mapping: an efficient and powerful methodology to reveal karyotypic and chromosomal evolution, pp. 513–523 Guilherme T. Braz, Li He, Hainan Zhao, Tao Zhang, Kassandra Semrau, Jean-Marie Rouillard, Giovana A. Torres, and Jiming Jiang Development of a eukaryotic karyotype relies…
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To fight malnutrition, geneticists are developing more nutritious corn
Corn feeds millions of people, and its low cost makes it particularly important in developing countries. However, it can’t be relied on as the sole source of protein for either humans or livestock because—like most cereals—corn is low in certain essential amino acids. In the 1960s, a type of corn was discovered with boosted levels of…