A better way to make endogenous reporters in C. elegans CRISPR systems for gene editing have revolutionized biological research, but the method still has limitations....
An analysis of the acknowledgment sections of theoretical population genetics papers from the 1970s and 1980s reveals overlooked contributions of women to the foundation of...
A new genome assembly for Antarctic fur seals sheds light on their historic comeback after 19th century hunting. In the late 19th century, the Antarctic...
Conservation BiologyFundamental ResearchG3 JournalGenomicsMammalsPopulation GeneticsVertebrates
Sexual reproduction is scarce in skin infection culprit. While some people love to feel the burn during a workout, we generally seek that sensation in...
Fundamental ResearchFungiGenetics JournalGenetics of SexHuman DiseaseMicrobesPopulation Genetics
An evolutionary approach outperforms a design approach in modeling protein sequence variation. Over generations, evolution shapes proteins, leading to variation in their amino acid sequences...
A suppressor screen in C. elegans uncovers previously unknown flexibility in the genetics underlying extracellular membranes. In nearly all animal tissues, thin barriers called basement...
C. elegansFundamental ResearchGenetics JournalModel Organisms
New evidence for genome instability in fly tumors suggests key similarities—and differences—from human disease processes. Human cancers display a variety of abnormal genomic features, including...
Cancer GeneticsDrosophilaFundamental ResearchG3 JournalHuman DiseaseModel Organisms
Offshoot of the modENCODE project provides crucial data and strains for understanding gene regulation. Following a multidisciplinary effort spanning six institutions, researchers working on the modERN...
C. elegansData & DatabasesDrosophilaGene ExpressionGenetics JournalModel Organism DatabasesModel Organisms
A new fruit fly model of Leigh syndrome reveals the importance of mtDNA variation. Inherited mitochondrial disorders pose a perplexing problem to researchers and clinicians:...
DrosophilaFundamental ResearchGenetics JournalHuman DiseaseModel OrganismsRare Diseases
Photosensitive alternative splicing of a malt fly circadian clock gene varies between northern and southern populations. Over the course of a day, most organisms undergo...
DrosophilaEvolutionFundamental ResearchG3 JournalGene ExpressionInsects