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Articles by Sejal Davla (16 results)
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Sejal Davla is a freelance science writer and data scientist with expertise in neuroscience and genetics. She is a motivated storyteller and works on projects at the intersection of science, data, and policy.
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Gain or loss? Time to rethink how we describe gain-of-function mutations
Characterizing how mutations bring about phenotypic changes is a common strategy for identifying molecular underpinnings. A perspective article in GENETICS challenges the way researchers categorize mutations as gain-of-function and advises how to avoid misleading labeling.
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A new study highlights the need for considering spatial structure in detecting positive selection
Identifying the signatures of natural selection in a population is tricky. A new simulation-based model investigates how population structure affects our ability to accurately predict signatures of selective sweeps.
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Determining causative alleles underlying the link between Epstein-Barr virus and multiple sclerosis
New research published in G3 identifies genetic risk variants of multiple sclerosis in immune cells, with many alleles relevant in EBV infection.
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Mapping the natural history of yeast in a science outreach program
New research published in G3: Genes|Genomes|Genetics lays out a geographical sampling activity tailored for middle school students that helps discover genetic diversity in yeast populations residing in North American oaks.
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Lost in translation: Mistranslated tRNA variants show sex-specific effects in Drosophila
A Drosophila model of protein mistranslation reveals the effects of serine to valine (V→S) and serine to threonine (T→S) substitutions on development, survival, and longevity where not all effects are detrimental to flies.
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Science & PublishingNew method reveals hidden evolutionary signatures in human non-coding genomic regions
Research published in G3 showcases a new approach that incorporates multiple demographic parameters and the distribution of fitness effects to understand human evolutionary history.
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A detailed recombination map reveals sex-specific differences in recombination rates in barn owls
The first recombination landscape of barn owls, published in GENETICS, quantifies sex-dependent variation in recombination and identifies differences in fine-scale patterns among chromosomes and populations.
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Science & PublishingThe power of genetic screening: identifying genes that alter nervous system shape in Drosophila
New results published in G3 summarize the genetic pathways controlling nervous system structure and explore how a single gene regulates tissue shape in a cell-type specific manner.
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Science & PublishingChew on this: improved greater wax moth genome gives insight into plastic biodegradation
New reference genome published in G3 supports phylogenetic exploration of plastic degrading enzymes produced by winged insects.
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Science & PublishingBalancing genetic privacy with open data in genomic research
A new encryption method published in GENETICS allows researchers to maintain human data confidentiality without the need for decryption in genomic analyses.
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A microbiologist’s quest to understand CRISPR in bacterial self-defense
2024 Genetics Society of America Medal recipient Luciano Marraffini determined how CRISPR-Cas systems destroy genetic targets with precision, paving the way for gene editing technology development.