Inheriting an extra chromosome can sometimes be disastrous, but in the September issue of G3, Linder et al. investigate a chromosome duplication that helps yeast...


When a group of microorganisms needs to stick together, they build a biofilm. The cells cement themselves together onto a surface, forming durable structures that...


As in real estate, so in cell biology: location is key. Knowing where a protein localizes in a cell gives insight into its function, and...


Two highly similar genes that contribute to drug resistance in a pathogenic yeast have been co-evolving as tandem duplicates for the past 134 million years—while...


Restricting calorie intake seems to promote longer lives in a wide range of organisms, from microbes to mammals. Some determined youth-seekers are already adopting reduced-calorie...


One of the last places you’d expect to find a charged amino acid residue is buried within the hydrophobic interior of a lipid bilayer. And...


Deep within a tumor, sequestered from an adequate blood supply, a cancer cell grows and multiplies. Far beneath Earth’s surface, a microbe lives and thrives...


To the unaided eye, Antarctic soil and alpine glaciers may appear to be barren wastelands devoid of life. But some microbes call hostile habitats like...


Cancer profoundly scars the genome of an affected cell. Amplification and overexpression of chunks of DNA sequence are common—but it’s not always clear whether these...


In the late 1980s, Japanese biologist Yoshimori Ohsumi finally got to run a lab of his own and began casting around for a suitable topic...