Take two neighboring cells from the same tissue—cells that are about as identical as any could be. Despite their similarities, these two cells could actually...


Restricting calorie intake seems to promote longer lives in a wide range of organisms, from microbes to mammals. Some determined youth-seekers are already adopting reduced-calorie...


One of the last places you’d expect to find a charged amino acid residue is buried within the hydrophobic interior of a lipid bilayer. And...


The arms race between pathogens and their hosts leaves clear genetic marks: the most quickly evolving parts of host genomes often include immune genes. But...


Off the coast of North America drifts a jellyfish that has unknowingly revolutionized molecular biology. Aequorea victoria produces green fluorescent protein (GFP), a substance that...


The chicken is one of humanity’s closest and oldest allies. With a worldwide population in the billions, this former jungle fowl is one of the...


Deep within a tumor, sequestered from an adequate blood supply, a cancer cell grows and multiplies. Far beneath Earth’s surface, a microbe lives and thrives...


Misfolded proteins can be so toxic that they cause cell death. At least nine neurodegenerative disorders are caused by misfolded proteins with expanded stretches of...


To boost transcription of a target gene, enhancer sequences must make contact with the gene’s promoter. This crucial meeting is mediated by interacting proteins and...


Each year, emergency departments in the US treat almost 700,000 people for traumatic brain injury (TBI). The outcome depends largely on the severity and location...