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The evolution of protein design
An evolutionary approach outperforms a design approach in modeling protein sequence variation. Over generations, evolution shapes proteins, leading to variation in their amino acid sequences both between and within species. Despite our ever-increasing knowledge of the physical constraints that guide protein structure, advanced modeling techniques don’t capture the site-specific variability observed in natural proteins. Bafflingly,…
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Fall 2018 DeLill Nasser Awardees
GSA is pleased to announce the recipients of the DeLill Nasser Award for Professional Development in Genetics for Fall 2018! Given twice a year to graduate students and postdoctoral researchers, DeLill Nasser Awards support attendance at meetings and laboratory courses. The award is named in honor of DeLill Nasser, a long-time GSA supporter and National Science Foundation Program…
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Videos from PEQG18 Keynote and Crow Award sessions
Watch presentations from the conference, including talks from Katie Peichel and Jonathan Pritchard. Now that the dust has settled from the whirlwind of the first ever standalone GSA Population, Evolutionary, and Quantitative Genetics Conference (PEQG18), we’re delighted to be able to share the audio and synched slides from the Keynote and Crow Award sessions. We’re…
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Namrata Sengupta on believing in the power of your own story
Science Communications Officer Namrata Sengupta is building a career at the Broad Institute of MIT and Harvard by breaking down complex science for the public. Crafting her PhD training, she transitioned from conducting research to aiding scientists in sharing their research stories. In the Decoding Life series, we talk to geneticists with diverse career paths, tracing the…
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Early Career Leadership Spotlight — Jaclyn Bubnell
We’re taking time over the following weeks to get to know the members of the GSA’s Early Career Scientist Committees. Join us every week to learn more about our early career scientist advocates. Jaclyn Bubnell Diversity Subcommittee Cornell University Research Interest Genetic variation provides a species opportunities to adapt to its…
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An updated tool for finding the footprints of selection
diploS/HIC uses machine learning to identify selective sweeps in unphased data. A set of footprints can tell us a lot about the creature that left them—without requiring us to see the creature itself. Footprints can suggest the animal’s size, weight, and stride, and from there, we can extrapolate even more information. Much like soft sand…
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#PEQG18 GSA Poster Award Winners
Congratulations to all the winners of poster awards at the 2018 Population, Evolutionary, and Quantitative Genetics Conference! Graduate Students Matthew Osmond University of British Columbia Poster title: Genetic paths to evolutionary rescue Paloma Medina University of California, Santa Cruz Poster title: Estimating the Prevalence of Wolbachia Across Arthropod and Nematode Taxa Ankeeta Shah University of…
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The Alaska Sea Grant State Fellowships: an inside view
This post is part of the Early Career Scientist Policy Subcommittee’s series on science policy fellowships. The Alaska Sea Grant State Fellowship Program is an opportunity for recent graduate students to spend a year working at a state or federal agency in Alaska on projects at the intersection of marine science and policy. Fellows are…
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Haley Hunter-Zinck: You don’t have to make career decisions alone
As a Health Science Specialist at the VA Boston Healthcare System, Haley Hunter-Zinck combines her bioinformatics skills with her passion for helping people create tools that help doctors make decisions on patient care. In the Decoding Life series, we talk to geneticists with diverse career paths, tracing the many directions possible after research training. This series is…
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Early Career Leadership Spotlight — Laura Taylor
We’re taking time over the following weeks to get to know the members of the GSA’s Early Career Scientist Committees. Join us every week to learn more about our early career scientist advocates. Laura Taylor Policy Subcommittee University of Washington Research Interest Alzheimer’s Disease and other related dementias, collectively known as…
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Imprinting impulsivity
Imprinted genes can have oppositional effects on adult behavior in mice. Mammalian genomes show the marks of a genetic tug-of-war between mothers and fathers. These imprinted genes are marked by epigenetic modifications, which means the expression of an imprinted allele depends on whether it was inherited from the mother or the father. A new report…