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Articles tagged Genetics Journal
(301 results)
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GSA journals partner with bioRxiv
Today we announced good news for our authors who use the bioRxiv preprint server! In partnership with Cold Spring Harbor Laboratory, the GSA journals GENETICS and G3 are rolling out a new feature that allows authors to submit their manuscript for peer review at one of our journals and, if they choose, simultaneously post it…
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Distal eQTLs, angry rats & zebrafish sex: November GENETICS highlights
The November issue of GENETICS is out today! Check out the highlights below or the full Table of Contents here. Genetic influences on brain gene expression in rats selected for tameness and aggression, pp. 1277–1290 Henrike O. Heyne, Susann Lautenschläger, Ronald Nelson, François Besnier, Maxime Rotival, Alexander Cagan, Rimma Kozhemyakina, Irina Z. Plyusnina, Lyudmila Trut, Örjan…
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GSA Award Essays
Check out the GSA award winners’ essays in this month’s issue of GENETICS! GENETICS SOCIETY OF AMERICA MEDAL Unanticipated Success Stories: An Interview with Angelika Amon “I would argue that under some circumstances, studying yeast cells is a better idea than studying highly transformed human cells in a dish.” THOMAS HUNT MORGAN MEDAL…
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Rare disease expert Kym Boycott joins the GENETICS editorial board
We’re pleased to announce that Kym Boycott (Children’s Hospital of Eastern Ontario) has joined the GENETICS Editorial Board. Following Editor-in-Chief Mark Johnston’s call for submissions of human genetics research, Dr. Boycott is a welcome addition to the board’s growing list of editors with expertise in human genetics. Dr. Boycott is a Medical Geneticist at the Children’s Hospital of Eastern Ontario…
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Zebrafish models for one-of-a-kind families
In this month’s editorial, the Editors of GENETICS invite submissions of human genetics research articles. To kick off the journal’s call for papers, the October issue features an article by Brooks and Wall et al. identifying the cause of a single-family disorder and a commentary by Phil Hieter and Kim Boycott on the power of model organisms…
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CRISPR Cleans Up
A versatile new CRISPR/Cas9 genome editing strategy allows mutation, tagging, and gene deletion in C. elegans without the use of co-integrated markers or long homology arms, report Paix et al. in an article published Early Online in GENETICS. The strategy can be easily scaled up, and should allow systematic construction of precise ORF deletions and…
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Fine-Mapping Diabetic Traits with Outbred Rats
In 1979, as the US slid into recession, researchers began systematically crossing eight distinct inbred rat strains. Their goal was to establish a genetically diverse rat colony to serve as a base for phenotype measurements and artificial selection. But the creators of the NIH rat Heterogeneous Stocks (HS) faced major challenges: “…the main one being…
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Does neural crest development drive domestication syndrome?
In Stellenbosch, South Africa, in the shade of the university botanical gardens, Adam Wilkins and Richard Wrangham drank coffee and worked their way through a list. Tameness. Smaller muzzles. Smaller teeth. Patches of white fur. Floppy ears. In early 2011, Wilkins, Perspectives editor at GENETICS, and Wrangham, primatologist at Harvard, were both spending the semester…
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Genetic maps, 100 years later
One feverish night, just over 100 years ago, an undergraduate in Thomas Hunt Morgan’s lab created the first genetic map. Realizing that the frequency of crossing over could be used to work out out the linear order of genes on a chromosome, that student, Alfred Sturtevant, published his map in 1913 and laid the foundation…
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The Fragile Y
Y chromosomes have come and gone many times during evolutionary history. Take beetles. When Heath Blackmon and Jeff Demuth modeled sex chromosome evolution in more than a thousand beetle species, they found the Y chromosome had independently evolved around 65 times in the suborder Adephaga alone. And as fast as this group evolved new Y chromosomes,…
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More Bang for your GWAS Buck
For genome-wide association studies, data is power. The more data you have, the more statistical power you wield to find genetic associations. But are there ways to get more from the data you already have? In the May issue of GENETICS, Kaufman and Rosset describe a testing framework that substantially boosts the power of genome-wide…