Articles tagged Genetics Journal
(305 results)

By the time President Obama announced the Precision Medicine Initiative in January 2015, the Genetic Epidemiology Research on Adult Health and Aging (GERA) cohort was already a trailblazing example of this new approach to medical research. GERA is a group of more than 100,000 members of the Kaiser Permanente Medical Care Plan who consented to…

Patients seeking certainty in genetic tests, such as tests for inherited susceptibility to cancer, often receive a perplexing result. Many people learn they carry a “variant of unknown significance” of a disease-linked gene. Such variants might—or equally might not—increase disease risk. In the latest issue of GENETICS, Starita et al. characterized nearly 2000 variants of…

The June issue of GENETICS is out now! Check out the Highlights below or the full Table of Contents here.   ISSUE HIGHLIGHTS Cortical folding of the primate brain: an interdisciplinary examination of the genetic architecture, modularity, and evolvability of a significant neurological trait in pedigreed baboons (Genus Papio), pp. 651–665 Elizabeth G. Atkinson, Jeffrey Rogers,…

The vibrant passion-vine butterfly species Heliconius erato doesn’t taste as good as it looks. The flesh of this South and Central American species accumulates toxic compounds to discourage would-be predators, who quickly learn to associate the butterflies’ unpleasant taste with their bold red warning colors and patterns. But H. erato isn’t the only species that…

The May issue of GENETICS is out now! Check out the highlights below or the full Table of Contents here. Efficient multiple-trait association and estimation of genetic correlation using the matrix-variate linear mixed model, pp. 59–68 Nicholas A. Furlotte and Eleazar Eskin Existing approaches to multiple-trait association mapping are computationally intractable for large sample sizes, limiting their…

In 2009, after five years parching under the arid blue skies of Calcena in northeastern Spain, dozens of neat rows of maritime pine seedlings had grown unevenly. Some of the seedlings had died years ago, some were stunted but hanging on, while others grew tall and green. The trees were not in their native soil.…

From animal domestication to human genome variation, from loblolly genomes to lager genomes, from wild zebrafish sex to untangled metagenomes, last year brought plenty of high points for the GSA journals. So gathering a small selection of those high points into the 2014 Spotlight booklets was a challenging, but rewarding task for the editors of GENETICS…

The April issue of GENETICS is out now! Check out the highlights below of the full Table of Contents here. Nascent transcription affected by RNA polymerase IV in Zea mays, pp. 1107–1125 Karl F. Erhard Jr., Joy-El R. B. Talbot, Natalie C. Deans, Allison E. McClish, and Jay B. Hollick RNA polymerase IV (Pol IV) is required…

Last week, GENETICS published an editorial by Editor-in-Chief Mark Johnston about the influence of the Journal Impact Factor on science and discussed an alternative metric that emphasizes the research experience of the journal’s editors. The following is Mark’s response to some of the feedback he’s received: In my editorial I proposed a new metric for…

The March issue of GENETICS is out now! Check out the highlights below of the full Table of Contents here.   Locally epistatic genomic relationship matrices for genomic association and prediction, pp. 857–871 Deniz Akdemir and Jean-Luc Jannink In breeding studies a distinction is made between the genetic value (additive + epistatic genetic effects) and…

Whether your computer screen displays a spreadsheet, a movie, or a LOLcat, you’re seeing  pinpoints of light in only three colors: red, green, and blue. But by varying the relative intensity of these three components, a pixel can transform into any one of a spectrum of millions of colors. The same principle lies behind the…