Articles tagged Genetics Journal
(301 results)

If you’ve ever watched a procedural crime-solving show on television, you’re sure to have seen a lab tech magically produce results from a complicated assay in mere minutes. If you’re a wet lab scientist, you’ve probably found yourself wishing that “CSI technology” were real so you didn’t have to spend your whole day running PCRs…

The January cover of GENETICS commemorates the journal’s 100th anniversary and the 1916 publication of Calvin Bridges’ proof that genes lie on chromosomes. The artwork was created by Alexander Cagan, a graduate student at the Max Planck Institute for Evolutionary Anthropology studying the genetics of domestication in rats. We spoke to Alex about the cover, his art, and his…

Celebrate our centennial by checking out the Highlights below or the full Table of Contents here! ISSUE HIGHLIGHTS This Month’s Centennial Articles A new century of GENETICS, pp. 1-2 Mark Johnston Editor-in-Chief Mark Johnston launches the second century of GENETICS and our year-long centennial celebrations. Sewall Wright on evolution in Mendelian populations and the “Shifting Balance,”…

Chickens that “chicken out” in unfamiliar surroundings may shed light on anxiety in humans, according to research published in the January 2016 issue of the journal GENETICS. Domestic chickens are much less anxious than their wild cousins, the red junglefowl. The new research identifies genes that contribute to this behavioral variation and reveals that several…

  In 1916, in the very first issue of GENETICS, Calvin Bridges published his proof that genes are carried on chromosomes. One hundred years later, genetics is again at the brink of a major transformation, as efficient genome engineering becomes a reality. During this century of incredible advances, GENETICS, published by the Genetics Society of…

With about 1 in 8 women in the United States expected to develop breast cancer in their lifetime, breast cancer remains the most common malignancy in women. Though heavily studied, its complexity creates significant challenges to diagnosis, prognosis, and treatment. One of the major problems is that causal DNA mutations of the disease vary from…

Compared to a human, a tree, or a jellyfish, the single-celled yeast might seem like a loner. Multicellular organisms like plants and animals are complex co-operative structures made of many specialized cell types, while a single yeast cell can survive and proliferate without the help of others. But although you might think of yeast as…

The December issue of GENETICS is out now! Check out the Highlights below or the full Table of Contents here. ISSUE HIGHLIGHTS The nature of genetic variation for complex traits revealed by GWAS and regional heritability mapping analyses, pp. 1601–1613 Armando Caballero, Albert Tenesa, and Peter D. Keightley Caballero et al. used simulations to show that, contrary to previous results, common…

The mutations that drive cancer formation are often found in “hub” genes that regulate many aspects of cell growth and survival. But these key genes are not always good therapeutic targets — some are even considered “undruggable.” In the latest issue of GENETICS, Bailey et al. identify a strategy for fighting cancer cells that carry…

What if we could eradicate malaria by engineering a mosquito population that doesn’t transmit the disease? What if we could control invasive species that outcompete natural populations? What if we could get rid of insecticide-resistant pests not by developing new chemical treatments, but instead by changing the population itself and driving it toward extinction? Although…

The November issue of GENETICS is out now! Check out the Highlights below or the full Table of Contents here. ISSUE HIGHLIGHTS A novel statistical model to estimate host genetic effects affecting disease transmission, pp. 871—884 Osvaldo Anacleto, Luis Alberto Garcia-Cortes, Debby Lipschutz-Powell, John A. Woolliams, and Andrea B. Doeschl-Wilson This article provides insight into how host genetic diversity affects…