The most diverse of all human genes encode a set of proteins at the frontline of our immune system. Many different Human Leukocyte Antigen (HLA)...
BioinformaticsG3 JournalGenomicsGWASHuman DiseaseImmune SystemPopulation GeneticsSequencing
With genomic data from hundreds of thousands of people accumulating, geneticists are now able to mine these data for very rare, but very informative genetic variants, including loss-of-function alleles. For example, across...
