Restricting calorie intake seems to promote longer lives in a wide range of organisms, from microbes to mammals. Some determined youth-seekers are already adopting reduced-calorie...


One of the last places you’d expect to find a charged amino acid residue is buried within the hydrophobic interior of a lipid bilayer. And...


Deep within a tumor, sequestered from an adequate blood supply, a cancer cell grows and multiplies. Far beneath Earth’s surface, a microbe lives and thrives...


To the unaided eye, Antarctic soil and alpine glaciers may appear to be barren wastelands devoid of life. But some microbes call hostile habitats like...


Cancer profoundly scars the genome of an affected cell. Amplification and overexpression of chunks of DNA sequence are common—but it’s not always clear whether these...


In the late 1980s, Japanese biologist Yoshimori Ohsumi finally got to run a lab of his own and began casting around for a suitable topic...


“This is the first self-replicating species that we’ve had on the planet whose parent is a computer. Because it’s very difficult to eliminate multiple genes...


Model Organism Databases (MODs) and the Gene Ontology Consortium play a crucial “behind-the-scenes” role in the work of model organism geneticists and many other biomedical...


Massive amplification of genes is a desperate strategy taken by stressed populations adapting to an environment that has become inhospitable. Such amplifications can give an...


Sequencing the genomes of hundreds of strains of the wine yeast S. cerevisiae has revealed little genetic diversity and high levels of inbreeding. In many...