A versatile new CRISPR/Cas9 genome editing strategy allows mutation, tagging, and gene deletion in C. elegans without the use of co-integrated markers or long homology...
In 1979, as the US slid into recession, researchers began systematically crossing eight distinct inbred rat strains. Their goal was to establish a genetically diverse...
Complex Traits & Quantitative GeneticsG3 JournalGenetics JournalHuman DiseaseMouse & Rat
In Stellenbosch, South Africa, in the shade of the university botanical gardens, Adam Wilkins and Richard Wrangham drank coffee and worked their way through a...
BehaviorDevelopmentDomesticationEvolutionGenetics JournalMammals
One feverish night, just over 100 years ago, an undergraduate in Thomas Hunt Morgan’s lab created the first genetic map. Realizing that the frequency of...
Y chromosomes have come and gone many times during evolutionary history. Take beetles. When Heath Blackmon and Jeff Demuth modeled sex chromosome evolution in more than...
For genome-wide association studies, data is power. The more data you have, the more statistical power you wield to find genetic associations. But are there...
Complex Traits & Quantitative GeneticsGenetics JournalGenomicsGWASHuman Disease
In Eurasia, humans once had Neanderthals for neighbors. That time of co-existence seems to have left its marks in our genome; non-Africans today share more genetic...
EvolutionGenetics JournalGenomicsHuman Evolution & VariationPopulation Genetics
Do aging males make poorer quality sperm? Older mothers face a well-established risk of producing eggs with chromosome abnormalities, but it is less clear how...
Transposable elements don’t proliferate in genomes at a steady pace; they often arrive in bursts. But models of neutral TE evolution assume transposition occurs at...
DrosophilaGenetics JournalPopulation GeneticsTransposable Elements
