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Articles tagged Genetics Journal
(301 results)
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March GENETICS Highlights
Check out the March issue of GENETICS by looking at the highlights or the full table of contents! ISSUE HIGHLIGHTS Simultaneous modeling of disease status and clinical phenotypes to increase power in genome-wide association studies, pp. 1041-1047 Michael Bilow, Fernando Crespo, Zhicheng Pan, Eleazar Eskin, and Susana Eyheramendy Jointly modeling clinical phenotype and disease status is a promising…
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A single gene controls multiple feeding-related traits in fruit fly larvae
Fruit fly larvae have one goal: eat as much as possible. After the tiny worm-like larvae hatch from eggs embedded into the flesh of rotting fruit, they eat their way out. After days of gorging, they find a good spot to pupate and then emerge as adults. Fruit flies cannot grow after this transformation, however,…
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Behind the Cover: Attack of the 50 Foot Mosquito
When geneticist Rob Unckless took his son to Lego Club at the local library, he was not expecting to start a new collaboration. The result is the striking piece of science-inspired art that graces the cover of the February issue of GENETICS. Created by artist Kent Smith, “Attack of the 50 Foot Mosquito” was inspired…
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The unique genetic variation of the Greenlandic Inuit population could help find novel disease associations
Despite being covered by a massive, permanent ice sheet, Greenland has been continuously inhabited by humans for over a thousand years. Most modern Greenlanders are Inuit whose ancestors migrated eastward from Canada around 1000 AD, bringing technology like kayaks and dogsleds. They eventually settled on the coasts of the world’s largest island, hunting whales and…
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Rapid immune evolution: exception or rule?
The arms race between pathogens and their hosts leaves clear genetic marks: the most quickly evolving parts of host genomes often include immune genes. But are these fast-movers the exception among immune genes, or do most genes in this class bear the genetic signature of strong selection? In the January issue of GENETICS, Early et…
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February GENETICS Highlights
Check out the February issue of GENETICS by looking at the highlights or the full table of contents! ISSUE HIGHLIGHTS Feeding-related traits are affected by dosage of the foraging gene in Drosophila melanogaster, pp. 761-773 Aaron M. Allen, Ina Anreiter, Megan C. Neville, and Marla B. Sokolowski The foraging gene has been implicated in multiple feeding-related traits. Allen…
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A modern look at ancient DNA
Well over 15,000 years ago, a man and a bear died in a cave in the Jura Mountains in modern-day Switzerland. That was the end of the story for millennia—until their remains were discovered in 1954 by researchers investigating the cave. Further work in the 1990s uncovered the fact that the man had, in fact,…
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January GENETICS Highlights
Check out the January issue of GENETICS by looking at the highlights or the full table of contents! ISSUE HIGHLIGHTS This Month’s Centennial Articles The sustained impact of model organisms—in genetics and epigenetics, pp. 1-4 Nancy M. Bonini and Shelley L. Berger In this GENETICS Centennial commentary, Nancy M. Bonini and Shelley L. Berger reflect on the history of…
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The tiny worm with a big impact
These worms are as long as a pencil’s tip and only just visible without a microscope. They are among the smallest multicellular animals, but they still have complex organ systems. They are Caenorhabditis elegans, one of the most important organisms in modern biology and a key to understanding the most basic molecular processes of life.…
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The fungus-fighting secrets hiding in the sugar pine’s enormous megagenome
Towering sugar pine trees dominate the mountain forests of California and Oregon. They are the tallest pine trees in the world, regularly growing to skyscraper heights of over 100 meters. But these forest behemoths are under attack from a very tiny foe: an invasive fungus. White pine blister rust was accidentally introduced to western North…
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New schizophrenia risk genes found by computational analysis
Symptoms of schizophrenia most commonly begin to creep up in young adulthood. Although genetics play a major role in this complex disorder, narrowing down the search for the genes involved has proven frustratingly difficult. Risk loci identified by genome-wide association studies (GWAS) may contain several genes, making it unclear which of these contribute to pathology.…