We are pleased to announce the launch of a new section: Functional Genomics and Systems Biology. This section will highlight experimental and computational studies that explore genetic and molecular interactions at the systems level—across pathways and networks—using genomic, transcriptomic, proteomic, and metabolomic data.

The section will feature papers that provide significant biological insights from diverse models, as well as new experimental or computational methods. Machine learning approaches and other innovative tools for understanding genetic mechanisms at a systems level will be welcome contributions.

Functional Genomics and Systems Biology will replace the current Genome and Systems Biology section, which has been led by Senior Editor Audrey Gasch. We thank Audrey for her outstanding leadership and service.

Senior Editors

The new section will be led by Brenda Andrews (University of Toronto) and Marian Walhout (UMass Chan Medical School).

Brenda Andrews headshot

Brenda Andrews is a University Professor in the Donnelly Centre for Cellular and Biomolecular Research and the Department of Molecular Genetics at the University of Toronto. She earned her PhD in Medical Biophysics at the University of Toronto and completed postdoctoral training in genetics with the late Ira Herskowitz at the University of California, San Francisco. Her laboratory uses genetic and genomic approaches to study conserved eukaryotic biology and genetic networks, primarily in yeast. Brenda has held multiple leadership roles at the University of Toronto and beyond, and her honors include being named a Companion of the Order of Canada, a Fellow of the Royal Society of Canada, the American Association for the Advancement of Science, and the American Academy of Microbiology, as well as an International Member of the US National Academy of Sciences. She served as the founding Editor-in-Chief of G3 and is currently President of the GSA Board of Directors.

Marian Walhout is the founding Chair of the Department of Systems Biology and Maroun Semaan Chair in Biomedical Research at UMass Chan. Her lab studies the interplay between metabolism and gene regulation using systems-level, network-based approaches and computational modeling. Much of her work leverages Caenorhabditis elegans and its bacterial diet as a model system to understand host–microbe interactions, nutrient effects, and molecular processes that regulate cellular functions.

Associate Editors

Four Associate Editors will also join the section:

  • Anne-Ruxandra Carvunis, University of Pittsburgh & ETH Zurich
  • Athma Pai, UMass Chan Medical School, Worcester
  • Leopold Parts, Wellcome Sanger Institute, Hinxton
  • Michael Brent, Washington University in St. Louis

This new section reflects the growing importance of systems-level research in genetics and genomics. We look forward to publishing studies that deepen our understanding of genetic networks, pathways, and interactions through integrative, cutting-edge approaches.

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