Enter your address to receive notifications about new posts to your email.
-
Worm101: Caenorhabditis elegans educational Primer
In time for the 20th International C. elegans Meeting, GENETICS has published the next in its series of model organism education Primers. Ann Corsi, Bruce Wightman, and Marty Chalfie introduce Caenorhabditis elegans and the many features that make it an outstanding experimental system. The authors describe the basic biology, genetics, anatomy, genomics, ecology, and evolution…
-
Turning spit and data into treasure
By the time President Obama announced the Precision Medicine Initiative in January 2015, the Genetic Epidemiology Research on Adult Health and Aging (GERA) cohort was already a trailblazing example of this new approach to medical research. GERA is a group of more than 100,000 members of the Kaiser Permanente Medical Care Plan who consented to…
-
Thousands of BRCA1 variants tested by deep mutational scanning
Patients seeking certainty in genetic tests, such as tests for inherited susceptibility to cancer, often receive a perplexing result. Many people learn they carry a “variant of unknown significance” of a disease-linked gene. Such variants might—or equally might not—increase disease risk. In the latest issue of GENETICS, Starita et al. characterized nearly 2000 variants of…
-
June GENETICS Highlights
The June issue of GENETICS is out now! Check out the Highlights below or the full Table of Contents here. ISSUE HIGHLIGHTS Cortical folding of the primate brain: an interdisciplinary examination of the genetic architecture, modularity, and evolvability of a significant neurological trait in pedigreed baboons (Genus Papio), pp. 651–665 Elizabeth G. Atkinson, Jeffrey Rogers,…
-
The molecules behind mimicry
The vibrant passion-vine butterfly species Heliconius erato doesn’t taste as good as it looks. The flesh of this South and Central American species accumulates toxic compounds to discourage would-be predators, who quickly learn to associate the butterflies’ unpleasant taste with their bold red warning colors and patterns. But H. erato isn’t the only species that…
-
New in G3: Mosquitoes, cotton, & CYCLoPs
Check out the June issue of G3! MEETING REPORT Meeting Report on Experimental Approaches to Evolution and Ecology Using Yeast and Other Model Systems Audrey P. Gasch and Gaël Yvert G3 June 2015 5:1021-1023; Early Online April 22, 2015, doi:10.1534/g3.115.018614 Full Text | Full Text (PDF) INVESTIGATIONS Analysis of RNA Interference Lines Identifies New Functions…