Cristy Gelling is a science writer, lapsed yeast geneticist, and former Communications Director at the GSA.
CRISPR’d worm: A Caenorhabditis elegans hermaphrodite glows green after insertion of GFP in K08F4.2, a gene expressed in the germ line and in embryos. A PCR fragment containing GFP flanked by 33-base pair homology arms was used to repair a CRISPR/Cas9 cut near the stop codon of K08F4.2. See Paix et al., 198: 1347–1356. Image courtesy of Alexandre Paix.

In time for the 20th International C. elegans Meeting, GENETICS has published the next in its series of model organism education Primers. Ann Corsi, Bruce Wightman, and Marty Chalfie introduce Caenorhabditis elegans and the many features that make it an outstanding experimental system. The authors describe the basic biology, genetics, anatomy, genomics, ecology, and evolution of the model, as well as the importance of the worm research community’s collaborative nature.

“A Transparent Window into Biology: A Primer on Caenorhabditis elegans”  is co-published with WormBook, the online review of C. elegans biology, and provides a concise introduction for students, educators, and others new to the field. The Primer serves as WormBook’s introductory chapter.


A Transparent Window into Biology: A Primer on Caenorhabditis elegans
Ann K. Corsi, Bruce Wightman, and Martin Chalfie
Genetics June 2015 200:387-407; doi:10.1534/genetics.115.176099

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