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Articles tagged Neuroscience
(29 results)
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Cause of neurological disorder in Belgian Shepherds discovered
Malinois dogs are working animals known for being used by the Secret Service to guard the White House. These dogs, a subtype of the Belgian Shepherd breed, are robust, with an average life expectancy of 10-12 years. But some puppies are afflicted by a genetic condition called spongy degeneration with cerebellar ataxia (SDCA). A puppy…
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How the genetics of seizure susceptibility changes over time
Epilepsy is characterized by recurrent seizures, often with no immediately obvious cause. In the August issue of G3, Ferland et al. use a genome-wide association study in mice to show that after multiple seizures, the genetic basis of seizure variation shifts from previously identified genomic regions to new ones. This research shows that the genetic…
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How nematodes sense danger
In critical situations, communication can mean the difference between life and death. If our house goes up in flames, we don’t need to smell smoke to be alarmed as long as someone yells, “Fire!” This isn’t unique to humans; even creatures with much less sophisticated means of sharing information have ways of telling each other…
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The tiny worm with a big impact
These worms are as long as a pencil’s tip and only just visible without a microscope. They are among the smallest multicellular animals, but they still have complex organ systems. They are Caenorhabditis elegans, one of the most important organisms in modern biology and a key to understanding the most basic molecular processes of life.…
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High Temperatures Suppress Seizures in a Fruit Fly Epilepsy Model
The human brain is an amazing machine powered by electricity. Carefully controlled patterns of changing electrical charges in neurons allow us to to think, move, and speak. When this system is disrupted, very bad things happen. A seizure occurs when a sudden surge of electrical activity in the brain interrupts normal functioning. Seizures are accompanied…
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Trying to Find your Way in the Nervous System? C. elegans can help!
Guest post by Daniel G. Taub. With billions of neurons in the human brain, making the right connections during development seems a daunting task. A developing neuron often follows the lead of trailblazers, using existing bundles of axons called axonal tracts as a guide. But how does the original axonal tract get laid down? In…
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Why flies forget: a molecular look at long-term memory
Memory is a complex neurological process, and understanding its mechanics rarely yields clear-cut answers. So far, research on the memory-implicated gene HDAC4 has been no exception—in fact, HDAC4’s effects on long-term memory seem completely contradictory. Increased HDAC4 protein in the cell nucleus causes memory deficits, and consistent with this, a human mutation that resulted in…
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Overly fastidious flies shed light on neurofibromatosis
Fruit flies that devote an excessive amount of time to grooming themselves could serve as a powerful tool for understanding the inherited disorder neurofibromatosis, type 1 (NF-1), report researchers in the latest issue of G3: Genes|Genomes|Genetics. NF-1 leads to the development of benign tumors in the peripheral nervous system. Common complications of NF-1…
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New Faculty Profile: Jennifer Garrison
New Faculty Profiles showcase GSA members who are establishing their first independent labs. If you’d like to be considered for a profile, please complete this form on the GSA website. Jennifer Garrison Assistant Professor Buck Institute for Research on Aging Lab website Research program: We study the relationship between the anatomy of neural…
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New Faculty Profile: Brent Neumann
New Faculty Profiles showcase GSA members who are establishing their first independent labs. If you’d like to be considered for a profile, please complete this form on the GSA website. Brent Neumann Senior Research Fellow Department of Anatomy and Developmental Biology Monash University Melbourne, Australia Lab website Twitter: @NeumannLab Research program: We use…
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An early TAGC abstract submission: Bess Frost
Bess Frost submitted the second abstract for The Allied Genetics Conference (TAGC), less than 30 minutes after the first submission. Find out more about her work and why she’s coming to TAGC. Bess Frost, PhD Assistant Professor Barshop Institute for Longevity & Aging Studies University of Texas Health Science Center at San Antonio Faculty…