Enter your address to receive notifications about new posts to your email.
Articles tagged Human Disease
(91 results)
-
Zebrafish models for one-of-a-kind families
In this month’s editorial, the Editors of GENETICS invite submissions of human genetics research articles. To kick off the journal’s call for papers, the October issue features an article by Brooks and Wall et al. identifying the cause of a single-family disorder and a commentary by Phil Hieter and Kim Boycott on the power of model organisms…
-
Fine-Mapping Diabetic Traits with Outbred Rats
In 1979, as the US slid into recession, researchers began systematically crossing eight distinct inbred rat strains. Their goal was to establish a genetically diverse rat colony to serve as a base for phenotype measurements and artificial selection. But the creators of the NIH rat Heterogeneous Stocks (HS) faced major challenges: “…the main one being…
-
More Bang for your GWAS Buck
For genome-wide association studies, data is power. The more data you have, the more statistical power you wield to find genetic associations. But are there ways to get more from the data you already have? In the May issue of GENETICS, Kaufman and Rosset describe a testing framework that substantially boosts the power of genome-wide…