Articles tagged C. elegans
(36 results)

A suppressor screen in C. elegans uncovers previously unknown flexibility in the genetics underlying extracellular membranes. In nearly all animal tissues, thin barriers called basement membranes anchor outward-facing layers of cells—the linings of lungs, the top layers of skin, the insides of blood vessels—to the connective tissues that support them. Mutations disrupting any major basement…

Offshoot of the modENCODE project provides crucial data and strains for understanding gene regulation. Following a multidisciplinary effort spanning six institutions, researchers working on the modERN (model organism Encyclopedia of Regulatory Networks) project have released a powerful resource for biologists studying the fruit fly Drosophila melanogaster and the nematode worm Caenorhabditis elegans. So far, report Kudron,…

Consider the papercut—a minor injury best known for the disproportionate amount of pain it can cause. That a wound so inconsequential can sting so terribly is curious, but perhaps even more surprising is the fact that it heals at all. To heal a wound, even one as trivial as a papercut, the cells involved in…

The fastest-evolving genes in eukaryotes commonly encode reproductive proteins—and the rate at which genes for male reproductive proteins change, in particular, often vastly outstrips the rate of change across the genome as a whole. A recent paper in G3: Genes|Genomes|Genetics describes an unusual exception: the amino acid sequences of the most abundant sperm proteins in…

The Genetics Society of America (GSA) is pleased to announce that Barbara Meyer is the recipient of the 2018 Thomas Hunt Morgan Medal, which is awarded for lifetime achievement in genetics. This honor is given in recognition of her groundbreaking work on chromosome behaviors that govern gene expression, development, and heredity. Meyer’s studies of how…

In the 1980s, scientists first noticed circles of DNA interspersed among the normally linear chromosomes of eukaryotic nuclei. Little is known about these molecules, which are called extrachromosomal circular DNA (eccDNA). Variation in eccDNA appears to be biologically significant; development of an organism often comes with increased numbers of eccDNA, for example, and certain types…

The Genetics Society of America’s Edward Novitski Prize recognizes a single experimental accomplishment or a body of work in which an exceptional level of creativity and intellectual ingenuity has been used to design and execute scientific experiments to solve a difficult problem in genetics. The 2017 winner, Jonathan Hodgkin, used elegant genetic studies to unravel…

When you catch a nasty cold, curling up in bed to sleep may be the only activity you can manage. Sleeping in response to stress isn’t a uniquely human behavior: many other animals have the same reaction, and it’s not clear why. While the circadian sleep that follows the pattern of the clock has been…

As night fell, astronomer Jean Jacques d’Ortous de Mairan watched a plant’s leaves, symmetrically arranged side-by-side on a stem, clamp shut. It was 1729, and he was studying the dramatic nocturnal movement of Mimosa pudica. Strangely, he found that the plant behaved the same way even when it wasn’t exposed to natural cycles of light…

Inheriting a trait from a grandparent doesn’t always involve their DNA sequences. In many organisms, some traits can be passed down for multiple generations via non-sequence based mechanisms, a phenomenon called transgenerational epigenetic inheritance. The most familiar example is that human disease risk might be influenced by the lifestyle of a person’s grandparents. But by…

For the past 20 years, Ahna Skop has organized the Worm Art Show at the 21st International C. elegans Conference. These are the winners from #Worm17, which was held in June 2017 at UCLA. Click on any image to view it full size. Best In Show “Do you expect me to talk?” Beata Mierzwa (BeataScienceArt.com), Oegema and Desai Lab…