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Science & Publishing
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Science & Publishing
#TAGC16 Shorts: What if gene expression timing matters more than abundance?
Guest post by Christian R. Landry. #TAGC16 Shorts are brief summaries of presentations at The Allied Genetics Conference, a combined meeting of seven genetics research communities held July 13-17, 2016 in Orlando, Florida. When building new phenotypes, evolution often draws on mutations of the intricate mechanisms that regulate gene expression. If such regulatory mutations are…
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Science & Publishing
#TAGC16 Shorts: the bursting bubble of harmful mutations
Guest post by Tyler Kent. #TAGC16 Shorts are brief summaries of presentations at The Allied Genetics Conference, a combined meeting of seven genetics research communities held July 13-17, 2016 in Orlando, Florida. Purging harmful mutations is the most common task of natural selection. In non-recombining populations this background selection process represents the “survival of the…
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Science & Publishing
#TAGC16 Shorts: evolution on ecological timescales
Guest post by Julia Kreiner. #TAGC16 Shorts are brief summaries of presentations at The Allied Genetics Conference, a combined meeting of seven genetics research communities held July 13-17, 2016 in Orlando, Florida. A common perception of evolution sees only slow and consistent genetic change over thousands of generations. But geneticists are increasingly shedding light on…
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Science & Publishing
Fast-growing bacteria doom their colonies’ attempts at resistance
Lurking in colonies of pathogenic bacteria are drug-resistant mutants. If the colony is exposed to antibiotics, these resistant mutants may survive, but they still face the challenge of recolonizing the host. Their success in this task depends on their diversity; a diverse population is more likely to harbor mutants that can withstand a second threat,…
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Science & Publishing
#TAGC16 Shorts: ancient roots of arthritis
#TAGC16 Shorts are brief summaries of presentations at The Allied Genetics Conference, a combined meeting of seven genetics research communities held July 13-17, 2016 in Orlando, Florida. Elbows, knuckles, and the other synovial joints in your body are mobile marvels of evolution. These joints allow a huge range of possible movements thanks to the presence of…
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Science & Publishing
Meet the editors at TAGC
Got a hot manuscript or a burning question for a GENETICS or G3 editor? Just want to talk about scholarly publishing in general? Here’s how you can track down an editor at The Allied Genetics Conference this week: Watch out for ribbons GENETICS and G3 Editors will be wearing silver “Editor” ribbons on their name…
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Science & Publishing
Genetic test helps ponies leave the past behind
For the past several decades, Shetland ponies’ collective past had caught up with them. A portion of the population of these miniature horses is affected by atavism, a phenomenon in which ancient characteristics are accidentally revived by mutations. Traits reincarnated in this way sometimes interact disastrously with the genetic background of the modern organism. For…
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Science & Publishing
Primers: Make friends with a new model organism
We hope everyone at The Allied Genetics Conference this week will take the opportunity to attend some presentations outside their “home” genetics community. But we realize that sometimes listening to talks in a new field can feel like visiting a foreign country, with its own language, unfamiliar customs, and insider jokes. If only you had…
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Science & Publishing
New in G3: Drosophila doublesex, Shetland pony SHOX, and SNP-SNP interactions
Check out the July issue of G3! ForestPMPlot: A Flexible Tool for Visualizing Heterogeneity Between Studies in Meta-analysis Eun Yong Kang, Yurang Park, Xiao Li, Ayellet V. Segrè, Buhm Han, and Eleazar Eskin G3 July 2016 6:1793-1798; Early Online May 18, 2016 doi:10.1534/g3.116.029439 Abstract | Full Text | Full Text (PDF) Sex Differences in Drosophila…
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Science & Publishing
July GENETICS Highlights
Check out the July issue of GENETICS by looking at the highlights or the full table of contents! This Month’s Centennial Articles Alfred Sturtevant and George Beadle untangle inversions, pp. 1001-1003 R. Scott Hawley and Barry Ganetzky R. Scott Hawley and Barry Ganetzky introduce Sturtevant and Beadle’s 1936 Classic that explained why inversion heterozygosity in the Drosophila X…
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Science & Publishing
Two-faced protein both speeds and slows cell cycle
Although some proteins have a single career, many—like Dis3—lead a double life. In the yeast Schizosaccharomyces pombe, loss-of-function mutations in dis3 cause defects in mitosis, implying that Dis3 normally supports cell cycle progression. But perplexingly, results in humans suggest that Dis3 normally slows cell cycle progression: mutations that partially disable dis3 contribute to the development…