Bruce Stewart Baker—the geneticist whose work uncovered molecular mechanisms of Drosophila sex determination and dosage compensation—died unexpectedly on July 1, 2018. He was 72. Bruce...


An automated drug screening approach gives insight into rare NGLY1 deficiency. Sometimes, diagnosing and treating an illness is straightforward. Other times, the diagnosis is challenging...


New evidence for genome instability in fly tumors suggests key similarities—and differences—from human disease processes. Human cancers display a variety of abnormal genomic features, including...


Offshoot of the modENCODE project provides crucial data and strains for understanding gene regulation. Following a multidisciplinary effort spanning six institutions, researchers working on the modERN...


A new fruit fly model of Leigh syndrome reveals the importance of mtDNA variation. Inherited mitochondrial disorders pose a perplexing problem to researchers and clinicians:...


Photosensitive alternative splicing of a malt fly circadian clock gene varies between northern and southern populations. Over the course of a day, most organisms undergo...


The Y chromosome has an unanticipated role in sex-biased intron retention in Drosophila. Differences between males and females in sexually dimorphic species stem in part...


Guest post by Thomas Kaufman in memory of Kathy Matthews. The original Drosophila Stock Center was housed at Cal Tech in Pasadena and was established...


Monomethylated H3K27 is more than just an intermediate. We often talk about biological traits as if they’re written in our DNA, but some of them...


Don’t miss out on this year’s Annual Drosophila Research Conference; check out the fantastic lineup of invited speakers below! The conference will be held April...