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Articles tagged Sequencing
(24 results)
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The trouble with HLA diversity
The most diverse of all human genes encode a set of proteins at the frontline of our immune system. Many different Human Leukocyte Antigen (HLA) proteins are encoded by genes clumped together in one portion of the human genome known as the major histocompatibility complex region. HLA proteins sit on the surface of cells and…
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Assembling a Colossus
The loblolly pine genome is big. Bloated with retrotransposons and other repetitive sequences, it is seven times larger than the human genome and easily big enough to overwhelm standard genome assembly methods. This forced the loblolly pine genome sequencing team, led by David Neale at the University of California, Davis, to look for ways to…