Science & Publishing

Check out the July issue of G3! INVESTIGATIONS Multiple Conserved Heteroplasmic Sites in tRNA Genes in the Mitochondrial Genomes of Terrestrial Isopods (Oniscidea) Christopher H. Chandler, Myriam Badawi, Bouziane Moumen, Pierre Grève, and Richard Cordaux G3 July 2015 5:1317-1322; Early Online April 24, 2015, doi:10.1534/g3.115.018283 Abstract | Full Text | Full Text (PDF) | Supporting…

Allelic expression in the mouse genome is surprisingly unbalanced, according to new research published in the June issue of GENETICS. The factors that determine how a gene is expressed in a given cell are complex. After all, every mammalian cell contains two copies of each gene, and both versions of that gene, called alleles, play…

The July issue of GENETICS is out now! Check out the Highlights below of the full Table of Contents here. And don’t miss the essays by winners of 2015 GSA Honors and Awards!   ISSUE HIGHLIGHTS Fine mapping causal variants with an approximate Bayesian method using marginal test statistics, pp. 719–736 Wenan Chen, Beth R.…

Check out the Genetics Society of America award winners’ essays in the July issue of GENETICS! The awardees share inspiration, observations, and predictions about their fields. Nominations are now open for the 2016 GSA awards through September 18.   Edward Novitski Prize Sue Biggins Under Tension: Kinetochores and Basic Research “It is […] easy to…

The Genetics Society of America and the GSA journals are pleased to welcome two new science writing interns to our team! Meet Sarah Bay and Kayleigh O’Keeffe; you’ll be seeing a lot of their writing right here at Genes to Genomes. We asked them to tell us a little about themselves: Sarah Bay: I’m a rising sixth year…

Directly observing evolution in nature is often impossible. But biologists who use experimental systems to study these processes have the luxury of observing the fine details directly, controlling the conditions, and even replicating the results. In the age of genomics, experimental approaches to ecology and evolution have become particularly powerful for genetic model systems, including…

In time for the 20th International C. elegans Meeting, GENETICS has published the next in its series of model organism education Primers. Ann Corsi, Bruce Wightman, and Marty Chalfie introduce Caenorhabditis elegans and the many features that make it an outstanding experimental system. The authors describe the basic biology, genetics, anatomy, genomics, ecology, and evolution…

By the time President Obama announced the Precision Medicine Initiative in January 2015, the Genetic Epidemiology Research on Adult Health and Aging (GERA) cohort was already a trailblazing example of this new approach to medical research. GERA is a group of more than 100,000 members of the Kaiser Permanente Medical Care Plan who consented to…

Patients seeking certainty in genetic tests, such as tests for inherited susceptibility to cancer, often receive a perplexing result. Many people learn they carry a “variant of unknown significance” of a disease-linked gene. Such variants might—or equally might not—increase disease risk. In the latest issue of GENETICS, Starita et al. characterized nearly 2000 variants of…

The June issue of GENETICS is out now! Check out the Highlights below or the full Table of Contents here.   ISSUE HIGHLIGHTS Cortical folding of the primate brain: an interdisciplinary examination of the genetic architecture, modularity, and evolvability of a significant neurological trait in pedigreed baboons (Genus Papio), pp. 651–665 Elizabeth G. Atkinson, Jeffrey Rogers,…

The vibrant passion-vine butterfly species Heliconius erato doesn’t taste as good as it looks. The flesh of this South and Central American species accumulates toxic compounds to discourage would-be predators, who quickly learn to associate the butterflies’ unpleasant taste with their bold red warning colors and patterns. But H. erato isn’t the only species that…