Enter your address to receive notifications about new posts to your email.
-
Beyond BRCA: new players in breast cancer pathways discovered
Mutations that disrupt the gene BRCA2 dramatically increase the odds of developing breast and ovarian cancer—but such mutations aren’t enough to cause cancer on their own. To turn normal cells cancerous, some of BRCA2’s genetic interactors must also mutate. In an article recently published in GENETICS, Ding et al. sought to identify some of these genes.…
-
Grant writing and lab meetings prepared Nigel Delaney with skills that enhance his role in industry
Nigel Delaney, Vice President of Computational Biology at the startup GenePeeks, talks about his transition from team member to manager and recommends PhD students remember the value of their training and time off when needed. In the Decoding Life series, we talk to geneticists with diverse career paths, tracing the many directions possible after research training. This series…
-
New in G3: mutant screens, Japanese quail evolution, and mating design in MAGIC sorghum
Check out the January issue of G3! Table of Contents Genome Report Reference Assembly and Annotation of the Pyrenophora teres f. teres Isolate 0-1 Nathan A. Wyatt, Jonathan K. Richards, Robert S. Brueggeman, Timothy L. Friesen G3: Genes, Genomes, Genetics January 2018 8: 1-8; DOI: https://doi.org/10.1534/g3.117.300196 Mutant Screen Reports Mapping Second Chromosome Mutations to Defined Genomic Regions in…
-
January GENETICS Highlights
Check out the January issue of GENETICS by looking at the highlights or the full table of contents! ISSUE HIGHLIGHTS Improving metabolic health through precision dietetics in mice, pp.399–417 William T. Barrington, Phillip Wulfridge, Ann E. Wells, Carolina Mantilla Rojas, Selene Y. F Howe, Amie Perry, Kunjie Hua, Michael A. Pellizzon, Kasper D. Hansen, Brynn H. Voy, Brian J. Bennett, Daniel…
-
Zebrafish offer hope for understanding severe form of epilepsy
The prolonged and severe seizures suffered by those with pyridoxine-dependent epilepsy (PDE) can lead to brain dysfunction and death if not treated. Standard antiepileptic drugs are typically ineffective for people with this rare genetic disorder—instead, they need high doses of vitamin B6 in the form of pyridoxine or pyridoxal 5′-phosphate. But even with this supplementation,…