Articles tagged Genomics
(78 results)

Leonid Kruglyak (HHMI/University of California, Los Angeles) has been awarded the 2016 Edward Novitski Prize for his extraordinary level of creativity and intellectual ingenuity in the solution of significant problems in genetics research. “Dr. Leonid Kruglyak has been a pioneer in human genetics for over 15 years…. he continues to pose questions and do experiments…

  Detlef Weigel (Max Plank Institute for Developmental Biology, Tuebingen) has been awarded the GSA Medal for his outstanding contributions to the field of genetics in the last 15 years. “Detlef’s blend of biology, genetics, and genomics technology has been key to many advances at the intersection of modern plant developmental and evolutionary biology”, said…

On November 11, 1954, Syuiti Mori turned out the lights on a small group of fruit flies. More than sixty years later, the descendents of those flies have adapted to life without light. These flies—a variety now known as “Dark-fly”—outcompete their light-loving cousins when they live together in constant darkness, according to research reported in…

Short-read sequencing has fueled the acceleration of genetic research But though these next-generation methods are fast and efficient, they can’t do everything well. One important area in which short-reads fall short is detecting structural variants (SV), where chunks of the genome are deleted, inserted, repeated, inverted, or in some other way shuffled around compared to…

An article in the most recent issue of Science highlights a growing concern about the continued support of the biological databases on which our community depends. Indeed, 2015 GSA President Jasper Rine was quoted as saying these resources are “critical for our daily life as geneticists and biomedical researchers.” Many of the model organism databases (MODs) used…

Amphibians around the world have been devastated by the spread of the deadly fungus Batrachochytrium dendrobatidis (Bd). But although many populations have been decimated, others have survived the same threat. One reason for such different outcomes is variation in virulence between Bd isolates. In the latest issue of G3, Refsnider and Poorten et al. investigate…

Johnny Kung, Director of New Initiatives for the Personal Genetics Education Project (pgEd), fills us in on their latest Congressional briefing. A version of this post is published on the pgEd website and is posted here with permission. On Nov. 17, our group, the Personal Genetics Education Project at Harvard Medical School, held a Congressional…

Today’s guest author is Emma Farley, a postdoctoral researcher in Mike Levine’s lab, which recently relocated to Princeton (formerly at University of California, Berkeley). Sea squirts (Ciona intestanalis) are a classic system for the study of development. They were a favorite of early developmental biologists like Laurent Chabry, Ed Conklin, and Thomas Hunt Morgan. Over…

Today’s guest author is Razib Khan, who is currently a graduate student in genomics at UC Davis. Outside of his scientific work he is interested in history, religion and philosophy, among other things. You can follow him on Twitter at https://twitter.com/razibkhan. If the story of the last century was the maturation of physical science, the plot of the coming…

Mark Blaxter (Institute of Evolutionary Biology, University of Edinburgh) reports on the “Caenorhabditis Genomes Project” workshop at GSA’s recent 20th International C. elegans Meeting. Caenorhabditis elegans, affectionately referred to as “the worm,” is one of the prettiest and most informative of the model organisms. It is see-through, has a simple lifecycle and a remarkably simple anatomy,…

Technical tips and progress on worm CRISPR/Cas9 genome engineering   Today’s guest post was contributed by Mike Boxem, Daniel Dickinson, and Alexandre Paix. Mike Boxem is a group leader at Utrecht University. His interests include technology development, systems biology, and cell polarity. Daniel Dickinson is a postdoctoral research fellow at the University of North Carolina.  His interests include…