Articles tagged Genetics Journal
(307 results)

With about 1 in 8 women in the United States expected to develop breast cancer in their lifetime, breast cancer remains the most common malignancy in women. Though heavily studied, its complexity creates significant challenges to diagnosis, prognosis, and treatment. One of the major problems is that causal DNA mutations of the disease vary from…

Compared to a human, a tree, or a jellyfish, the single-celled yeast might seem like a loner. Multicellular organisms like plants and animals are complex co-operative structures made of many specialized cell types, while a single yeast cell can survive and proliferate without the help of others. But although you might think of yeast as…

The December issue of GENETICS is out now! Check out the Highlights below or the full Table of Contents here. ISSUE HIGHLIGHTS The nature of genetic variation for complex traits revealed by GWAS and regional heritability mapping analyses, pp. 1601–1613 Armando Caballero, Albert Tenesa, and Peter D. Keightley Caballero et al. used simulations to show that, contrary to previous results, common…

The mutations that drive cancer formation are often found in “hub” genes that regulate many aspects of cell growth and survival. But these key genes are not always good therapeutic targets — some are even considered “undruggable.” In the latest issue of GENETICS, Bailey et al. identify a strategy for fighting cancer cells that carry…

What if we could eradicate malaria by engineering a mosquito population that doesn’t transmit the disease? What if we could control invasive species that outcompete natural populations? What if we could get rid of insecticide-resistant pests not by developing new chemical treatments, but instead by changing the population itself and driving it toward extinction? Although…

The November issue of GENETICS is out now! Check out the Highlights below or the full Table of Contents here. ISSUE HIGHLIGHTS A novel statistical model to estimate host genetic effects affecting disease transmission, pp. 871—884 Osvaldo Anacleto, Luis Alberto Garcia-Cortes, Debby Lipschutz-Powell, John A. Woolliams, and Andrea B. Doeschl-Wilson This article provides insight into how host genetic diversity affects…

This month, the GSA journal GENETICS published an editorial that illuminates the struggles experienced by scientists when trying to both do good science and advance in their career, especially as it relates to the unintended effects of the Journal Impact Factor (JIF). The editorial by Executive Editor Tracey DePellegrin and Editor-in-Chief Mark Johnston is largely intended to…

GENETICS’ publication of WormBook in the 21st century is a perfect partnership, because C. elegans research began in GENETICS with the May 1974 publication of Sydney Brenner’s The Genetics of Caenorhabditis elegans – the foundational article that launched an entire field. Since then, some of the most important papers about C. elegans have appeared in…

Publishing research in one of the GSA Journals as an undergraduate is a significant and valuable authorship experience and we want to hear your story (even if it was published years ago!). GSA’s Spotlight on Undergraduate Research showcases GENETICS and G3: Genes|Genomes|Genetics authors who were undergraduates when contributing to their paper. Sarah Radford Postdoctoral Associate, Rutgers University…

The effects of neurodegenerative diseases can be devastating for patients and their families. In 2007, the United Nations stated that 1 in 6 people in the world are affected by neurological disorders including diseases like Huntington’s, Alzheimer’s, and amyotrophic lateral sclerosis (ALS). With over 600 characterized neurological disorders yet very few treatments, it is imperative…

GSA dedicates these inaugural chapters to Bill Gelbart, who is dearly missed, and who will live on in our memories and in our work. Bill was an early enthusiast of the FlyBook project, and without his and Thom Kaufman’s vision to partner with GENETICS, these articles would not have the valuable richness of links to…