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Gain or loss? Time to rethink how we describe gain-of-function mutations
Characterizing how mutations bring about phenotypic changes is a common strategy for identifying molecular underpinnings. A perspective article in GENETICS challenges the way researchers categorize mutations as gain-of-function and advises how to avoid misleading labeling.
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Featured
Developmental biologist chases big questions in a tiny fly
Michael O’Connor, recipient of the 2026 Edward Novitski Prize, tackles challenging questions in Drosophila development, following where the science takes him.
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Featured
Yeast geneticist behind the 1,002 Yeast Genomes Project builds resources to connect genotypes to phenotypes
Joseph Schacherer, recipient of the 2026 GSA Medal, began exploring yeast genome diversity as a postdoctoral researcher. Now, his work, which grew to a total of 1,011 sequenced yeast genomes, serves as a springboard for a number of studies.
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Featured
From Arabidopsis to Zea mays, there’s a knowledgebase for that
In 2022, GENETICS debuted its first annual overview of selected knowledgebases. In continuance of that tradition, this year’s piece will discuss 12 knowledgebase updates with an emphasis on economically important plant Model Organism Databases (MODs). MODs, which first appeared in the 1990s, are sophisticated knowledgebases that aim to organize and integrate heterogeneous published knowledge for…
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Featured
Landing a faculty position: Dr. Morgan Carter
Interviews from newly appointed faculty members shed light on the path to landing a faculty position.
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Being a staff scientist offers C. elegans researcher the perfect balance between research and mentorship
Irini Topalidou, recipient of the 2026 GSA Mentorship Award, emphasizes the important role staff scientists play in academic research and mentoring.
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Featured
Don’t bug me, I’m at “The Fly Conference”
I thought I was attending the 67th Annual Drosophila Research Conference, but somehow ended up at a rock-and-roll concert. Fly Board President Eric Lai opened the meeting with an electric guitar riff. Luckily, his lyrics confirmed I was in the right place: “Don’t you know that the fly… is fly! It’s not an ask or…









