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Articles by Guest Author (205 results)
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Guest posts are contributed by members of our community. The views expressed in guest posts are those of the author(s) and are not necessarily endorsed by the Genetics Society of America. If you'd like to write a guest post, e-mail communications@genetics-gsa.org.
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An automated analytical pipeline for solving the GWAS puzzle
A new bioinformatic GWAS pipeline enables automated, multi-faceted analysis of the
combinatorial effect of multiple variants on a genetic trait. -
A year in a Drosophila lab, measured in carbon
Research published in GENETICS breaks down the total carbon emissions from a PhD student’s research, giving insights into where sustainability efforts matter most.
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New study suggests Elg1-RLC strays from the beaten path to safeguard replication stress
A new study in GENETICS reveals how the PCNA unloader Elg1-RLC protects replication forks during DNA damage, operating in a noncanonical pathway that safeguards genome stability when checkpoint signaling is compromised.
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The great genetic swap: Rethinking essentiality in fruit fly reproduction
The word “essential” carries weight in genetics: lose the gene, lose the function. Luke Arnce, Jaclyn Bubnell, and Charles Aquadro challenge this intuition in a recent focused comparative study of germline stem-cell (GSC) biology across Drosophila species in G3:Genes|Genomes|Genetics. They tested the famed bag-of-marbles (bam) gene for its conserved function as a switch for daughter…
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Re-introducing David Hogness, a pioneer of molecular genetics and developmental biology.
Nowadays, we don’t think twice about running a Q-PCR to check the expression of our favorite gene, or to sequence a genomic region to identify a mutation that causes an interesting phenotype. In contrast, 50 years ago, it could take an entire PhD to accomplish such a task. Molecular genetics has evolved at an exponential…
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Hold the salt: Study shows standard worm food NaCl levels accelerate aging
A new study in GENETICS has a “circuitous” origin story, according to equal investigator Brian M. Egan. When Egan showed Kerry Kornfeld his inconclusive Caenorhabditis elegans data on how varying concentrations of sodium chloride (NaCl) affect the anti-aging activity of the blood pressure drug captopril, Kornfeld noticed an unexpected difference in the controls. Since C.…
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Barcoding for Success
G3’s latest issue features two articles that improve researchers’ ability to untangle complex interactions between genes, drugs, and environmental factors.
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Telomeres outside the Goldilocks zone cause problems for yeast and humans
A new study in GENETICS investigates the role of generational inheritance of long telomeres in yeast cells.
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How Drosophila can help health science labs do more with less in Brazil
In Brazil, the FlyPower group has been promoting and advocating for biomedical Drosophila research in diverse ways, and shown that fly culture can be up to seven times cheaper than mammalian cell culture.
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Genes in context: How lifestyle and socioeconomic conditions shape the genetics of complex traits
Two new studies published in GENETICS explore how lifestyle and social context influence our understanding of complex health traits like blood pressure
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The little worm that could (escape light): a single nerve cell helps C. elegans escape harmful UV exposure
It’s hard to imagine, but the tiny, translucent roundworm called C. elegans has approximately 20,470 protein-coding genes—about the same number as humans. This is perhaps one of the many reasons why this common worm was the first multicellular organism to have its genome completely sequenced during the Human Genome Project in 1998. Studying C. elegans…