One feverish night, just over 100 years ago, an undergraduate in Thomas Hunt Morgan’s lab created the first genetic map. Realizing that the frequency of...


When Scott Alper and colleagues looked for candidate regulators of mammalian innate immunity based on gene expression data, the hit rate was only around 2%....


The Fragile Y

June 18, 2014

Y chromosomes have come and gone many times during evolutionary history. Take beetles. When Heath Blackmon and Jeff Demuth modeled sex chromosome evolution in more than...


For genome-wide association studies, data is power. The more data you have, the more statistical power you wield to find genetic associations. But are there...


In Eurasia, humans once had Neanderthals for neighbors. That time of co-existence seems to have left its marks in our genome; non-Africans today share more genetic...


The medaka, or Japanese rice fish, is a century-old genetic model on the rise again. Long studied by scientists in Japan, it has been rediscovered...


Sea Anemone & Friends

February 19, 2014

Coral reefs around the world are “bleaching”, a threat caused by breakdown of the symbiosis between the coral animals (cnidaria) and the dinoflagellate algae that...


Do aging males make poorer quality sperm? Older mothers face a well-established risk of producing eggs with chromosome abnormalities, but it is less clear how...