Imprinted genes can have oppositional effects on adult behavior in mice. Mammalian genomes show the marks of a genetic tug-of-war between mothers and fathers. These...


The “hyperspin” long-range enhancer deletion recapitulates disease phenotypes. In recent years, improvements in genetic testing have made it much easier to discover the causes of...


A reanalysis of genes tied to life span in mice reveals only a select few affect aging. Like it or not, you are always getting...


Biologists rely on animal models to answer important questions that can’t be addressed with cells in a dish. Often, these animals are deliberately inbred; a...


After surviving breast cancer, almost forty percent of female patients are affected by primary ovarian insufficiency (POI). This condition, in which ovaries don’t produce normal...


Epilepsy is characterized by recurrent seizures, often with no immediately obvious cause. In the August issue of G3, Ferland et al. use a genome-wide association...


Fascinating discoveries sometimes emerge from the most daunting of experimental roadblocks. Designed to generate over 1,000 recombinant inbred mice lines for genetic mapping, the Collaborative...


Multiparental populations (MPPs) have brought a new era in mapping complex traits, as well as new analytical challenges. To face these challenges and encourage innovation,...


Guest post by Teresa Bonello It was 1984 and the first cloning of the homeobox sequence in Drosophila had just been reported. Newly-minted postdoc Denis...


#TAGC16 Shorts are brief summaries of presentations at The Allied Genetics Conference, a combined meeting of seven genetics research communities held July 13-17, 2016 in...