Misfolded proteins can be so toxic that they cause cell death. At least nine neurodegenerative disorders are caused by misfolded proteins with expanded stretches of...


To boost transcription of a target gene, enhancer sequences must make contact with the gene’s promoter. This crucial meeting is mediated by interacting proteins and...


Each year, emergency departments in the US treat almost 700,000 people for traumatic brain injury (TBI). The outcome depends largely on the severity and location...


Symptoms of schizophrenia most commonly begin to creep up in young adulthood. Although genetics play a major role in this complex disorder, narrowing down the...


Recombination within the genome isn’t random. This swapping of DNA segments between one chromosome and its homolog preferentially affects specific genome regions called hotspots. These...


To the unaided eye, Antarctic soil and alpine glaciers may appear to be barren wastelands devoid of life. But some microbes call hostile habitats like...


Given the outcome of the US presidential election, some of our members have asked us if they should fear an erosion of federal support for...


Last week at The Allied Genetics Conference (TAGC), National Institutes of Health (NIH) Director Francis Collins provided an overview of model organism support from his...


Although some proteins have a single career, many—like Dis3—lead a double life. In the yeast Schizosaccharomyces pombe, loss-of-function mutations in dis3 cause defects in mitosis,...


Model Organism Databases (MODs) and the Gene Ontology Consortium play a crucial “behind-the-scenes” role in the work of model organism geneticists and many other biomedical...