Articles tagged Aging
(11 results)

By borrowing a system found in plants, researchers can turn off sperm production in an inducible, reversible, and non-toxic manner Let’s say you want to study how your favorite gene affects aging. You pick Caenorhabditis elegans for your study because it is one of the most important models of aging, and you put some of…

A reanalysis of genes tied to life span in mice reveals only a select few affect aging. Like it or not, you are always getting older. The mechanisms responsible for this fact of life, non-negotiable as it is, remain poorly understood. To identify genes that drive the aging process, researchers typically look for those that…

Multiparental populations (MPPs) have brought a new era in mapping complex traits, as well as new analytical challenges. To face these challenges and encourage innovation, the GSA journals launched the ongoing Multiparental Populations series in 2014. This month’s issues of GENETICS and G3 feature a bumper 16 MPP articles, timed to celebrate a new easy-to-use…

Restricting calorie intake seems to promote longer lives in a wide range of organisms, from microbes to mammals. Some determined youth-seekers are already adopting reduced-calorie diets in an attempt to extend their lifespans. But it’s not clear yet that these anti-aging effects apply to humans, and the mechanisms by which they work in other organisms…

New Faculty Profiles showcase GSA members who are establishing their first independent labs. If you’d like to be considered for a profile, please complete this form on the GSA website.   Jennifer Garrison Assistant Professor Buck Institute for Research on Aging Lab website   Research program: We study the relationship between the anatomy of neural…

New Faculty Profiles showcase GSA members who are establishing their first independent labs. If you’d like to be considered for a profile, please complete this form on the GSA website.   Xantha Karp Assistant Professor of Biology Central Michigan University Lab website   Research program: During aging, stem cells gradually become less effective at renewing tissue,…

Today’s guest post is contributed by Todd Plummer, a Research Associate in Gordon Lithgow’s lab at the Buck Institute for Research on Aging. Todd is a certified California Naturalist interested in the ecological relationships that affect wild strains of worms used as model organisms. Follow him on Twitter: @plumtodd  This post first appeared on SAGE, a blog focused on the science…

By the time President Obama announced the Precision Medicine Initiative in January 2015, the Genetic Epidemiology Research on Adult Health and Aging (GERA) cohort was already a trailblazing example of this new approach to medical research. GERA is a group of more than 100,000 members of the Kaiser Permanente Medical Care Plan who consented to…

Today’s guest post was contributed by Andreas Prokop, of the University of Manchester. Along with research on the cell biology of neurons during development and ageing, he is engaged in many science communication and outreach projects. Follow him on Twitter: @Poppi62 More than a century of intense research with the fruit fly Drosophila has arguably turned…

Fruit flies suffer from an image problem. Maybe it’s the alliteration in the name, or the association with bananas, but Drosophila have become a go-to target for politicians looking to ridicule wasteful public spending. In February, presidential candidate and US Senator Rand Paul (R-KY) questioned the NIH for spending: “…a million dollars trying to determine…

Do aging males make poorer quality sperm? Older mothers face a well-established risk of producing eggs with chromosome abnormalities, but it is less clear how age affects meiosis in males. In the February issue of GENETICS, Vrooman et al. investigated chromosome dynamics during spermatogenesis in mice of different ages. They found that meiotic errors increased…