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  • BI 6727, A Polo-like Kinase Inhibitor with Improved Pharmacokinetic Profile and Broad Antitumor Activity. Dorothea Rudolph, Martin Steegmaier, Matthias Hoffmann, Matthias Grauert, Anke Baum, Jens Quant, Christian Haslinger, Pilar Garin-Chesa and Günther R. Adolf. Clin Cancer Res May 1 2009 (15) (9) 3094-3102; DOI: 10.1158/1078-0432.CCR-08-2445

    Using yeast to expose cancer’s genetic vulnerabilities

    Cancer profoundly scars the genome of an affected cell. Amplification and overexpression of chunks of DNA sequence are common—but it’s not always clear whether these changes are directly involved in the disease or byproducts of some other malfunction. Further complicating the search for treatments, many genes that are altered in cancer cells are involved in…

  • GSA-Art: Joanne Topol

    Guest post by Joanne Topol. GSA-Art features the creative works of scientists. Read more in GSA President Stan Fields’ call for submissions. If you would like to submit your own work or nominate someone else’s, please send an email to GenesToGenomes@genetics-gsa.org with “GSA-Art” in the subject line. My art reflects inner feelings that cannot be accessed through analytic thought. These feelings are…

  • GSA-Art: Bianca Ruiz

    GSA-Art features the creative works of scientists. Read more in GSA President Stan Fields’ call for submissions. If you would like to submit your own work or nominate someone else’s, please send an email to GenesToGenomes@genetics-gsa.org with “GSA-Art” in the subject line. Bianca Ruiz is a graduate student rotating in the Fields lab at the University of Washington, Genome Sciences, who…

  • GSA Journals Spotlight 2015

    The GSA Journals, GENETICS and G3: Genes|Genomes|Genetics, are proud to present our annual Spotlight booklets for research published in 2015. Each Spotlight is a showcase of the excellent research and scholarship published over the course of the year, along with a selection of striking images submitted by our authors. Browse the 2015 GENETICS Spotlight. Browse the 2015 G3 Spotlight.      …

  • Genomic study of high school students from across Denmark reveals remarkable genetic homogeneity

    People from Denmark are genetically similar to each other no matter which part of the country they come from, report researchers in the journal GENETICS, a publication of the Genetics Society of America. Eight hundred Danish high school students contributed genetic material to the Where Are You From? project, and the data were used to…

  • Something in common

    According to a survey from the Pew Research Center, 33% of Americans believe that God created humans in their present form within the last 10,000 years and another 24% believe that God guided evolution over millions of years to create humans as they exist today. While scientists should respect people’s deeply held religious beliefs, it…

  • New in G3: glucose biosynthesis, neural tube defects, and seizure suppression

    Check out the October issue of G3! Table of Contents Call for Papers Multiparental Populations: A Call for Papers G3 October 2016 6:3015; doi:10.1534/g3.116.035022 Full Text | Full Text (PDF) Investigations A Drosophila LexA Enhancer-Trap Resource for Developmental Biology and Neuroendocrine Research Lutz Kockel, Lutfi M. Huq, Anika Ayyar, Emma Herold, Elle MacAlpine, Madeline Logan,…

  • GSA-Art: Barbara Shih

    GSA-Art features the creative works of scientists. Read more in GSA President Stan Fields’ call for submissions. If you would like to submit your own work or nominate someone else’s, please send an email to GenesToGenomes@genetics-gsa.org with “GSA-Art” in the subject line. To me, science is not about being in the lab; it is about solving puzzles. I have been working…

  • October GENETICS Highlights

    Check out the October issue of GENETICS by looking at the highlights or the full table of contents! ISSUE HIGHLIGHTS This Month’s Centennial Articles Fumio Tajima and the origin of modern population genetics, pp. 389–390 Rasmus Nielsen Associate Editor Rasmus Nielsen introduces Fumio Tajima’s 1983 Classic on coalescence. This was one of the founding papers of modern population genetics…

  • Genome of fiercely protective Fonni’s Dog reflects human history of Sardinia

    A genomic analysis of 28 dog breeds has traced the genetic history of the remarkable Fonni’s Dog, a herd guardian endemic to the Mediterranean island of Sardinia. The results, published in this month’s issue of GENETICS, reveal that the regional variety has developed into a true breed through unregulated selection for its distinctive behavior, and that…

  • GSA-Art: Matthew Sachs

    GSA-Art features the creative works of scientists. Read more in GSA President Stan Fields’ call for submissions. If you would like to submit your own work or nominate someone else’s, please send an email to GenesToGenomes@genetics-gsa.org with “GSA-Art” in the subject line. Our first GSA-Art post is by Matthew S. Sachs, a Professor in the Department of Biology at Texas A&M University…